Currently I am running the following scanners:
- Avira Antivir
- Grisoft AVG
- F-Secure Blacklight
- Clamav
- BitDefender
Each of these give a different result for the same set of files. Some do not see any viruses and some see different than others. So if you are running just with one Antivirus solution, it might not bee enough to be safe. I can't say which of these would be the best or worst as they yield different result in different times. I am still about to test my favourite tool, F-Secure Antivirus, which in other hand is the most heaviest in using resources of my computer.